Puram Honored for Head and Neck Cancer Research – Washington University School of Medicine in St. Louis

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The Doris Duke Charitable Foundation rewards work on cancer immunotherapy


Sidharth V. Puram, MD, PhD, assistant professor of otolaryngology and director of the division of head and neck surgery at Washington University School of Medicine in St. Louis, received a development award from Doris Duke Charitable Foundation Clinical Scientist 2022. He is one of 16 early-career physician-scientists recognized for clinical research with the potential to have a strong impact on human health, including the prevention, diagnosis and treatment of disease. The award also supports young scientists in their transition to independent research careers.

Puram received the award for his research titled “Deciphering immunotherapy resistance in head and neck cancer using single-cell genomics and space-based techniques”. The project will study how head and neck cancers develop resistance to immunotherapy, a type of cancer treatment that harnesses the immune system to attack cancer cells. He will study the heterogeneity of these tumors and how tumor gene expression can differ in the 3D structure of the tumor.

Puram is also a surgeon who treats patients at the Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine. He specializes in the treatment and reconstruction of head and neck cancer, including mucosal disease, thyroid cancer, salivary gland disease, human papillomavirus (HPV) related tumors and head and neck skin cancers.


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